A tool that has already revolutionized disease research may soon get even better, thanks to an accidental discovery in the bacteria that cause many of the worse cases of meningitis. Called CRISPR-Cas9, the tool acts as molecular scissors that can cut DNA at exactly the spot they’re asked to. But the tool can’t cut the other kind of genetic material found in cells known as RNA. Now, researchers at the University of Michigan have discovered a single protein that can perform CRISPR-style, precise programmable cutting on both DNA and RNA. Continue to Full Article.
Molecular Cell paper from the Zhang lab (Biological Chemistry) reveals unexpected function for Cas9 from meningococcal bacteria
Feb 26, 2018 | News